That said, a study investigated the effect of raspberry ketones on adipose fat gain, liver fat storage, and adiponectin a protein hormone responsible for metabolic processes plasma levels in mice on a high-fat diet and found that supplementing raspberry ketones had a "limited benefit" for weight loss. Another study explored whether raspberry ketones would have any effect on white adipose tissue—fat that results from excess calorie intake—acquiring characteristics of brown adipose tissue, which generates heat by burning calories.
Researchers learned that raspberry ketones "significantly induced browning" of certain cells, reduced body weight gain, and limited food intake, among other benefits, in rats with obesity.
They concluded that the study's findings provided some evidence to support using raspberry ketones clinically to treat obesity. Currently, there is no reliable scientific evidence to support raspberry ketones as a weight-loss supplement for humans. Stimulant-like effects, including increased heartbeat and high blood pressure, are not uncommon in people taking raspberry ketones.
Raspberry ketones may possibly have damaging effects on the heart muscle and teratogenic consequences abnormal fetal developments due to drugs, chemicals, or infections. They might also negatively interact with drugs used to treat diabetes and blood clotting medications like warfarin. Raspberry ketone supplements are available in capsule, tablet, liquid, and powder form.
The dosage varies from to milligrams per day, which is notably higher than what a person would consume in a regular serving of fruit or in the form of flavorings. Some brands that sell raspberry ketone supplements claim to be all-natural or state that their product is made with natural ingredients. These claims can be misleading, as most manufacturers use synthetic ketones.
Even though raspberry ketones are naturally found in raspberries, the amount found in a single raspberry is minuscule and expensive to obtain. When choosing a supplement, it's best to look for one that has been approved through a third-party verification company that has checked the quality of the product. As supplements do not require FDA approval to be sold, it is the manufacturer's responsibility to ensure that their product is of good quality and safe to consume.
Be wary of supplements that claim to be free from side effects, have the ability to fix a problem or cure a disease, or deem themselves to be completely and totally safe. Finally, adding raspberries to your diet is also an option. People often confuse raspberry ketones for having ketogenic effects as touted by the popular ketogenic diet. The keto diet aims to burn fat, rather than carbohydrates, through a process called ketosis.
Raspberry ketones do not have this effect. One small study showed that applying raspberry ketones topically in a cream may promote hair growth, but more research needs to be done to prove whether this is truly effective or not. There is no conclusive scientific evidence supporting the use of raspberry ketones as a weight loss supplement. Before starting raspberry ketones or any other weight loss supplement , be sure to speak with your doctor. If you are interested in losing weight, they can help you determine the best way for you.
Get nutrition tips and advice to make healthy eating easier. Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women. J Int Soc Sports Nutr. Anti-obese action of raspberry ketone. Life Sci. Food Funct. In another rat study , the rodents were fed a high-fat diet with differing amounts of raspberry ketones.
The rats that received more raspberry ketones burned more body fat and gained less fat tissue. A third study exposed fat cells in a test tube to raspberry ketones and found that the raspberry ketones stimulated the breakdown of the fat cells. I'll agree that this is all very interesting research, but it is also considered very preliminary research.
Before making health and weight-loss claims about a supplement, don't you think we should have some double-blind studies involving real humans showing actual results with specific amounts of the supplement and assuring safety for the person? As a registered dietitian, I do. But what about the claims I've seen on TV? When you hear raspberry ketone claims such as "slicing up fat molecules," "burning fat easier," or "weight-loss miracle," change the channel.
There is no evidence to back up these claims. There has been no testing to determine safety or dosage amounts. Read the fine print. If you have aging eyes like mine, pull out your "cheaters" and read the small print on the raspberry ketone bottle. This information has not been evaluated by the U. Food and Drug Administration, nor has it gone through the rigorous double-blind studies required before a particular product can be deemed truly beneficial or potentially dangerous and prescribed in the treatment of any condition or disease.
Supplements such as these are not evaluated by the Food and Drug Administration, unlike medications, which undergo rigorous testing. As raspberry ketones may reduce inflammation, they might also lower the risk of dementia. No studies have directly assessed the role of raspberries or raspberry ketones in humans who have dementia or have a higher risk of developing it. Some research has looked at how ellagic acid, a phytochemical in raspberries, affects the formation of amyloid plaques.
The study showed that ellagic acid might slow the development of plaques. If this is the case, eating whole raspberries may be more beneficial than taking raspberry ketones as a supplement. However, more research is necessary to confirm this potential benefit. As there have not been well-designed clinical trials involving humans, doctors and researchers do not know whether raspberry ketones are safe. Scientists are also unclear whether certain groups may be at greater risk of raspberry ketone side effects than others.
In one case , a woman using raspberry ketones experienced organ failure. She was also using other weight loss supplements, so doctors do not know whether raspberry ketones played a role. Isolated case reports suggest that ketones might cause side effects similar to those of supplements. These can include:. People considering using raspberry ketones should consult a doctor first. Speaking to a doctor before taking raspberry ketones is particularly important for people who:.
Women who are pregnant or breastfeeding should be especially skeptical of ketones. Children should not take weight loss supplements.
There is no approved dosage for raspberry ketones. However, research generally focuses on ketones as a specific percentage of the diet rather than a fixed dosage. People who want to try ketones at lower doses than supplements provide could try eating large quantities of raspberries.
Fresh raspberries contain ketones in their natural state, not synthetic ketones. They are also generally safe, though eating large amounts of any fruit can cause diarrhea in some people. There is no clinical data on potential drug interactions with raspberry ketones. Researchers have not yet conducted sufficient research to know how raspberry ketones might interact with other drugs. Therefore, people taking other medications should not take ketones, as this could be unsafe. There is no evidence that raspberry ketones cause weight loss in humans and no reason to believe that they work better than traditional weight loss strategies.
Although the existing body of research on the other health benefits of ketones is hopeful, researchers must conduct more trials to confirm the effects of these compounds on the body. People who hope to get the benefits of raspberry ketones without the risk should consider eating more raspberries. Those who want to try ketones in supplement form should consult a doctor or dietitian first.
The diet can have a significant impact on the brain's function. A brain-healthy diet, rich in antioxidants and omega-3 fatty acids, can boost memory….
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